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Season
- Late Show with David Letterman Season 1 1993-08-30
- Late Show with David Letterman Season 2 1994-08-29
- Late Show with David Letterman Season 3 1995-09-04
- Late Show with David Letterman Season 4 1996-09-02
- Late Show with David Letterman Season 5 1997-09-01
- Late Show with David Letterman Season 6 1998-08-31
- Late Show with David Letterman Season 7 1999-09-07
- Late Show with David Letterman Season 8 2000-08-21
- Late Show with David Letterman Season 9 2001-08-20
- Late Show with David Letterman Season 10 2002-09-03
- Late Show with David Letterman Season 11 2003-09-01
- Late Show with David Letterman Season 12 2004-08-23
- Late Show with David Letterman Season 13 2005-08-29
- Late Show with David Letterman Season 14 2006-08-28
- Late Show with David Letterman Season 15 2007-09-04
- Late Show with David Letterman Season 16 2008-09-02
- Late Show with David Letterman Season 17 2009-08-31
- Late Show with David Letterman Season 18 2011-01-03
- Late Show with David Letterman Season 19 2012-01-03
- Late Show with David Letterman Season 20 2013-01-02
- Late Show with David Letterman Season 21 2014-01-06
- Late Show with David Letterman Season 22 2014-09-02
Episode
- Episode 1 : Amanda Peet, Tom Dreesen
- Episode 2 : Jeff Goldblum, George Miller
- Episode 3 : Drea de Matteo, Sarah Vowell, The Doves
- Episode 4 : Peter Jennings, John Witherspoon
- Episode 5 : John McEnroe, Piper Perabo, Queens of the Stone Age
- Episode 6 : Jennifer Esposito, Marianne Faithful
- Episode 7 : Bill Clinton, Nanci Griffith
- Episode 8 : Regis Philbin, Linda Thompson
- Episode 9 : Megan Mullally, Rich Hall
- Episode 10 : Bruce Willis, Eve
- Episode 11 : Jack Hanna, Tom Cavanagh, Civil War Reenactment
- Episode 12 : Reese Witherspoon, Juan Montoya, India.Arie
- Episode 13 : Rose McGowan, Phillipe Petit
- Episode 14 : Lauren Graham, Colin Quinn
- Episode 15 : Patricia Heaton, Murray Walker
- Episode 16 : David Schwimmer, Avril Lavigne
- Episode 17 : Anthony LaPaglia, Effie Nielson, Clinic
- Episode 18 : Edward Norton, John Mayer
- Episode 19 : David Arquette, Todd Lynn
- Episode 20 : Jennifer Love Hewitt, Tom Petty and The Heartbreakers
- Episode 21 : John McCain, David Sedaris
- Episode 22 : Charles Barkley, Franco Zeffirelli, Nitty Gritty Dirt Band
- Episode 23 : Michelle Pfeiffer, Bon Jovi
- Episode 24 : Johnny Knoxville, Ron White
- Episode 25 : Debra Messing, Pink
- Episode 26 : Thandie Newton, Faith Hill
- Episode 27 : Rudolph Giuliani, Naomi Watts
- Episode 28 : Samuel L. Jackson, Santana & Michelle Branch
- Episode 29 : P. Diddy, Eddie Brill
- Episode 30 : Bonnie Hunt, Christina Aquilera
- Episode 31 : Salma Hayek, Tori Amos
- Episode 32 : Warren Zevon
- Episode 33 : Jerry Seinfeld, Foo Fighters
- Episode 34 : Don Rickles, Jim Gaffigan
- Episode 35 : Stupid Human Tricks, Sean Hayes, Willie Nelson & Ryan Adams
- Episode 36 : Julianne Moore, Grant Paulsen, Blind Boys of Alabama
- Episode 37 : Kid Inventors, Tom Brokaw, The Wallflowers
- Episode 38 : Brittany Murphy, Al Lubel
- Episode 39 : Robin Williams, Emily Proctor
- Episode 40 : Kelly Ripa, Emmitt Smith, Missy Elliott
- Episode 41 : Barbara Walters, Joe Pantoliano
- Episode 42 : Maggie Gyllenhaal, Pearl Jam
- Episode 43 : Al Gore, Pearl Jam
- Episode 44 : Kevin James, matchbox 20
- Episode 45 : Shania Twain, Cristiano da Matta
- Episode 46 : Adam Sandler, Pussycat Dolls
- Episode 47 : Ice Cube, Cast of Hairspray
- Episode 48 : Harry Connick Jr., Larry Miller
- Episode 49 : Stupid Pet Tricks, Lisa Kudrow, Audioslave
- Episode 50 : George Clooney, Jack Hanna
- Episode 51 : Ray Romano, Jurassic 5
- Episode 52 : Amy Sedaris, The Strokes
- Episode 53 : Liza Minnelli, Jann Karam
- Episode 54 : Jennifer Lopez, Sum 41
- Episode 55 : Jason Alexander, Ryan Adams
- Episode 56 : Nia Vardalos, Barry Sonnenfeld
- Episode 57 : Allison Janney, Martin Scorsese
- Episode 58 : Natasha Richardson, Mike Birbiglia, David Gray
- Episode 59 : Catherine Zeta-Jones, Coldplay
- Episode 60 : Drew Barrymore, Rod Stewart
- Episode 61 : Denzel Washington, Daniel Bouloud
- Episode 62 : Tom Hanks, Phish
- Episode 63 : Liv Tyler, Jay Thomas, Darlene Love
- Episode 64 : Ashton Kutcher, Jason Kidd
- Episode 65 : Isabella Rossellini, Mort Sahl
- Episode 66 : Michael Caine, George Foreman
- Episode 67 : Richard Gere, Chris Elliott
- Episode 68 : Merv Griffin, Interpol
- Episode 69 : Renee Zellweger, Chuck Barris
- Episode 70 : Andy Richter, Rich Hall
- Episode 71 : Jimmy Kimmel, Simon Baker
- Episode 72 : Claire Danes, Bob Sarlatte
- Episode 73 : Sandra Bullock, Marv Albert
- Episode 74 : George Clooney, Soundtrack of Our Lives
- Episode 75 : Joan Rivers, Kathleen Edwards
- Episode 76 : Simon Cowell, Topher Grace, Vienna Teng
- Episode 77 : Regis Philbin, John C. Reilly
- Episode 78 : Tina Fey, Jonathan Ames, Johnny Marr & The Healers
- Episode 79 : Ellen DeGeneres, Zwan
- Episode 80 : Bonnie Hunt, John Witherspoon
- Episode 81 : Show #1944Kate Hudson, Jack Hanna
- Episode 82 : Matthew McConaughey, John Gruden, The Roots
- Episode 83 : Kelsey Grammer, Michael Tong, B.B. King and Shemeika Copeland
- Episode 84 : Stupid Pet Tricks, Tom Brokaw, The Pretenders
- Episode 85 : Brendan Fraser, Kids in The Hall, Bonnie Raitt, Keb' Mo, Kim Wilson
- Episode 86 : Matthew Broderick, Tony Bennett & k.d. Lang
- Episode 87 : Amy Brennamen, Nate Erwin, Vince Gill
- Episode 88 : Queen Latifah, Colin Quinn, Lou Reed
- Episode 89 : Kid Scientists, Kurt Russell
- Episode 90 : Kate Winslet, Dennis Regan, Rufus Wainwright
- Episode 91 : Dr. Phil, Beck
- Episode 92 : Vince Vaughn, Sarah Vowel, Beck
- Episode 93 : Kevin Spacey, Reggie Miller
- Episode 94 : Champion Turkey Callers, Marg Helgenberger, The Flaming Lips
- Episode 95 : Jeff Daniels, Lynne Cox, Steven Wright
- Episode 96 : Steve Martin, Foo Fighters
- Episode 97 : Stupid Human Tricks, Sharon Osborne, Norah Jones
- Episode 98 : Bruce Willis, Dan Rather, Carmen Electra, Brian Kiley
- Episode 99 : John McEnroe, Tom Arnold, Eric Ripert, Todd Barry, Jason Mras
- Episode 100 : Regis Philbin, Charles Grodin, Susan Lucci, Greg Giraldo, Kathleen Edwards
- Episode 101 : Whoopi Goldberg, Jessica Lange, Dave Chappelle, Andy Vistola, Ben Harper
- Episode 102 : Vince Vaughn, Rosie Perez, Geri Halliwell, Dwayne Kennedy, Paul Simon
- Episode 103 : Elvis Costello, Kim Cattrell, Eddie Izzard, Mitch Hedberg
- Episode 104 : Will Ferrell, Chris Rock, Crispin Glover, Jake Johannsen, American Hi-Fi
- Episode 105 : Megan Mullally, Molly Shannon, Isaac Mizrahi, Bonnie McFarlane
- Episode 106 : Brad Garrett, Cuba Gooding Jr., Julie Bowen, Reggie McFadden, Lyle Lovett
- Episode 107 : Tom Dreesen, Kiefer Sutherland, Frank Gershin, Suzanne Westenhoefer, The Music
- Episode 108 : Bonnie Hunt, Carson Daley, Eddie Griffin, Ron Beth-Israel, Fabolous
- Episode 109 : Paul Schaffer, Bob Dole, Connie Nielsen, Jeff Foxworthy, Cat Power
- Episode 110 : Bill Cosby, Andrew Firestone, Clark Tery, Sofia Vergara, The DA
- Episode 111 : Luke Wilson, Kelly Preston, Taye Diggs, Hilary Burton, Seether
- Episode 112 : Billy Crystal, Michael Barimo
- Episode 113 : Colin Farrell, Rosanne Cash
- Episode 114 : Helen Hunt, Jeremy Suarez, Cory Branan
- Episode 115 : High-Jumping Dogs, Vin Diesel, Bo Diddley
- Episode 116 : Hilary Swank, Jimmie Walker
- Episode 117 : Adam Sandler, The Folksmen
- Episode 118 : Lisa Marie Presley, Jamie Kennedy
- Episode 119 : Jane Krakowski, Jim Boeheim, Pete Yorn
- Episode 120 : Tom Brokaw, Tom Russell & Nanci Griffith
- Episode 121 : Michael Douglas, Todd Rundgren
- Episode 122 : Anthony LaPaglia, Brian Regan, The Exies
- Episode 123 : Ashton Kutcher, Jack Hanna
- Episode 124 : Ellen DeGeneres, John Malkovich
- Episode 125 : Charlize Theron, Sue Johanson, Minus 5 with Wilco
- Episode 126 : Bernie Mac, Amanda Peet
- Episode 127 : Halle Berry, Don Rickles
- Episode 128 : Kelly Rippa, Good Charlotte
- Episode 129 : Stupid Human Tricks, Hugh Jackson, Kelly Clarkson
- Episode 130 : David Hyde Pierce, Rube Goldberg Contest Winners, Ziggy Marley
- Episode 131 : Megan Mullally, Marilyn Manson
- Episode 132 : Albert Brooks, Jeffery Ross, The Libertines
- Episode 133 : Stupid Pet Tricks, Kevin James, Jenna Morasca
- Episode 134 : David Williams & Ronald Young, Jada Pinkett Smith, The Jayhawks
- Episode 135 : Sean Hayes, Eric Ripert, Avril Lavigne
- Episode 136 : Rene Zellweger, Jack Johnson
- Episode 137 : John Goodman, D.H. Hughley, NAS with Alicia Keys
- Episode 138 : Mark Wahlberg, Jesse James, the Sounds
- Episode 139 : Jim Carrey, Chevelle
- Episode 140 : Regis Philbin, 3 Doors Down
- Episode 141 : Antonio Banderas, Heidi Klum, Liam Lynch
- Episode 142 : Peter Krause, Jim Gaffigan, Widespread Panic
- Episode 143 : Adrien Brody, Gil de Ferran, John Mellencamp
- Episode 144 : Alec Baldwin, Tom Dreesen
- Episode 145 : Seth Green, Amy Sedaris, Lucinda Williams
- Episode 146 : Barbara Walters, Tanya Streeter
- Episode 147 : Tom Arnold, Darrell Hammond, Karolina Kurkova, Eddie Brill, Train
- Episode 148 : Juliette Binoche, Joe Queenan, Blur
- Episode 149 : Bruce Willis, Chris Moneymaker
- Episode 150 : Lauren Graham, Marv Albert, Bright Eyes
- Episode 151 : Harrison Ford, Annie Lennox
- Episode 152 : Tom Green, Jolene Blalock, Scott Stevens, Isaac Britty, Damien Rice
- Episode 153 : Hilary Clinton, Emmylou Harris
- Episode 154 : Rob Reiner, Paul Teutul Sr. & Jr., The New Pornographers
- Episode 155 : Johnny Depp, Christine Todd Whitman, B.B. King
- Episode 156 : Sarah Jessica Parker, The Dead
- Episode 157 : Kelsey Grammer, Treat Williams, James Earl Jones, Jamie Lynn-Sigler, Kathleen Madigan, Jesse Malin
- Episode 158 : Demi Moore, Verbana
- Episode 159 : Drew Barrymore, Simon Cowell
- Episode 160 : Lucy Liu, Avigayil Wardein, Nick Cave and The Bad Seeds
- Episode 161 : Piedmont Bird Callers, Luke Wilson, The Yeah Yeah Yeahs
- Episode 162 : Jimmy Fallon, Kristanna Loken, Dax, Chloe Sevigny, Bill Scheft, Rufus Wainwright
- Episode 163 : Lisa Marie Presley, Ryan Pinkston
- Episode 164 : Allison Janney, Nigella Lawson, Howard Tate
- Episode 165 : Barry Zito, Mandy Moore, Grandaddy
- Episode 166 : Ari Fleischer, Beyonce Knowles
- Episode 167 : Jeff Bridges, Alan Harvey, Joseph Arthur
- Episode 168 : Aron Ralston, Tobey Maguire
- Episode 169 : National Hollerin' Champions, Kristin Davis, Jane's Addiction
- Episode 170 : Joaquin Phoenix, Blues Traveler
- Episode 171 : Sylvester Stallone, Ben Curtis
- Episode 172 : Denis Leary, Queens of the Stone Age
- Episode 173 : Jesse Grabow, Jason Biggs, Robert C. Nichol
- Episode 174 : Eugene Levy, Eels
- Episode 175 : Seann William Scott, Jonathan Ames, Fountains of Wayne
- Episode 176 : Melanie Griffith, Pamela Reed
- Episode 177 : Naomi Watts, Jeff Stilson, O.A.R.
- Episode 178 : Kate Hudson, Cast of Camp
- Episode 179 : Colin Farrell, Robert Randolph & The Family Band
- Episode 180 : Samuel L. Jackson, Rick Reilly, Pharrell with Clipse
- Episode 181 : Brittany Murphy, Carey Hart, Dashboard Confessional
- Episode 182 : David Duchovny, Brett Butler, The New Amsterdams
- Episode 183 : Chris Rock, The Star Spangles
- Episode 184 : Bill Murray, Pete Sampras
- Episode 185 : David Spade, Bob Sarlatte, Maroon 5
- Episode 186 : Tony Hawk, John McEnroe, Rooney
- Episode 187 : Bonnie Hunt, Don Gavin
Late Show with David Letterman - Season 10 Episode 72
Dave announces that today is the 3rd anniversary of his quintuple bypass, and upon mentioning this, Regis interrupts the jokes to give Dave a quick check-up. ""You're screwed,"" Regis proclaims. Throughout the night, Dave reflects on the bypass, claiming he ran five miles six weeks after the bypass. Near the end of the show, Dave tells former announcer Bob Sarlette that his cholesterol is a healthy 46.
First Air Date: Aug 30, 1993
Last Air date: May 20, 2015
Season: 22 Season
Episode: 4252 Episode
Crew: David Letterman (Writer)
Cast: David Letterman, Paul Shaffer, Alan Kalter
Country: United States of America
Studio: CBS
Keyword: late-night show
Subtitle:
ETC.
ETC.
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